| Rank | Team | Pitchers Strikeouts | Record |
| 1. | Brooklyn Dodgers, 1934 | 441 | 63-91 |
| 2. | St. Louis Cardinals, 1938 | 453 | 65-89 |
| 3. | Philadelphia A's, 1948 | 460 | 64-90 |
| 4. | Pittsburgh Pirates, 1941 | 462 | 65-89 |
| 5. | Boston Braves, 1934 | 466 | 61-93 |
| 6. | Cincinnati Reds, 1944 | 473 | 84-70 |
| 7. | Cincinnati Reds, 1945 | 490 | 77-77 |
| 8. | Washington Senators, 1941 | 500 | 72-82 |
| 9. | Boston Braves, 1942 | 501 | 60-94 |
| 10. | Philadelphia A's, 1943 | 504 | 51-103 |
| 11. | Chicago Cubs, 1934 | 505 | 73-81 |
| 12. | Detroit Tigers, 1938 | 506 | 86-68 |
| 13. | Philadelphia A's, 1941 | 509 | 86-68 |
| 14. | Chicago Cubs, 1941 | 511 | 69-85 |
| 15. | St. Louis Browns, 1935 | 513 | 56-98 |
| 16. | Boston Braves, 1935 | 516 | 54-100 |
| 17. | Philadelphia A's, 1938 | 519 | 64-90 |
| 18. | Pittsburgh Pirates, 1938 | 519 | 61-93 |
| 19. | Boston Braves, 1933 | 520 | 82-72 |
| 20. | St. Louis Cardinals, 1934 | 526 | 94-60 |
| 21. | Boston Braves, 1941 | 533 | 75-79 |
| 22. | Brooklyn Dodgers, 1933 | 535 | 84-70 |
| 23. | Chicago Cubs, 1933 | 536 | 52-102 |
| 24. | Boston Braves, 1940 | 536 | 78-76 |
| 25. | Boston Red Sox, 1942 | 536 | 102-52 |
| 26. | New York Giants, 1938 | 537 | 99-55 |
| 27. | New York Giants, 1941 | 538 | 63-91 |
| 28. | New York Giants, 1948 | 538 | 67-87 |
| 29. | Chicago White Sox, 1943 | 540 | 87-67 |
| 30. | Boston Braves, 1938 | 543 | 81-73 |
| 31. | St. Louis Browns, 1934 | 545 | 62-92 |
| 32. | Boston Red Sox, 1938 | 546 | 67-87 |
| 33. | Pittsburgh Pirates, 1943 | 546 | 71-83 |
| 34. | Boston Braves, 1945 | 547 | 76-78 |
| 35. | Washington Senators, 1948 | 548 | 62-92 |
| 36. | Philadelphia A's, 1933 | 550 | 79-75 |
| 37. | New York Giants, 1934 | 550 | 77-77 |
| 38. | Chicago White Sox, 1947 | 553 | 71-83 |
| 39. | Philadelphia A's, 1954 | 553 | 59-95 |
| 40. | Philadelphia A's, 1937 | 554 | 78-76 |
| 41. | Pittsburgh Pirates, 1950 | 555 | 70-84 |
| 42. | Boston Red Sox, 1933 | 556 | 62-92 |
| 43. | Chicago White Sox, 1938 | 558 | 82-72 |
| 44. | Pittsburgh Pirates, 1947 | 559 | 86-68 |
| 45. | Chicago White Sox, 1944 | 560 | 72-82 |
| 46. | Chicago White Sox, 1945 | 561 | 73-81 |
| 47. | Boston Red Sox, 1941 | 565 | 101-53 |
| 48. | Pittsburgh Pirates, 1948 | 566 | 75-79 |
| 49. | Brooklyn Dodgers, 1938 | 567 | 77-77 |
| 50. | Brooklyn Dodgers, 1936 | 568 | 63-91 |